1 A DESIGN SPECIFICATION FOR THE CARDIOVASCULAR SYSTEM
  Oxygen consumption
  Carriage of oxygen in blood
  Cyanosis
  The battle against the hydrogen ion: acid-base
  balance
  Cell injury and cell death
  Overall functional structure of the cardiovascular
  system
  Circulation time
  Structure and function of blood vessels
  Angiogenesis
  From cradle to grave--the presentation of heart
  disease.
2 CARDIAC MUSCLE STRUCTURE AND FUNCTION
  Cardiac muscle
  Structure of cardiac muscle
  Contractile mechanism in cardiac muscle
  Cardiac electrical activity
  Drugs which act on the heart
3 THE HEART AS A PUMP: VALVE FUNCTION AND VALVE DISEASE
  Functional anatomy of the heart
  The cardiac cycle
  Valve pathology
  History taking for cardiac disease
  Clinical examination of the cardiovascular system
  Investigations of heart disease: imaging the heart
  Sudden cardiac death
4 REGULATION OF CARDIAC FUNCTION
  Introduction
  Venous return
  Control of cardiac output
  Regulation of heart rate
  Regulation of stroke volume
  Preload effects on the heart
  Contractility effects on the heart
  Afterload effects on the heart
  Summary
5 BLOOD SUPPLY TO THE HEART
  Anatomy of the arterial supply and venous drainage
  of the heart
  Regulation of coronary blood flow
  Ischaemic heart disease
  Thrombosis
  Angina
  Myocardial infarction
  Coronary angioplasty and stenting
  Coronary artery bypass grafting
6 HEART FAILURE
  Systolic vs diastolic failure
  Haemodynamic events
  Metabolic events in heart failure
  Neurohormonal aspects of heart failure
  Drug therapy for heart failure
7 THE ELECTROCARDIOGRAM (ECG)
  Introduction
  Producing a -lead ECG
  The components of the ECG trace
  Practical use of the ECG
  The ECG and rhythm disturbances
  Cardiac structure and the ECG
  Ischaemia and the ECG
  Potassium and the ECG
  Drugs and the ECG
8 LARGE BLOOD VESSELS
  Introduction
  Haemorheology: the physical characteristics
  of blood flow
  Pathology of arteries and veins
  Atherosclerosis
  Vasculitis
  Varicose veins
  Vascular pathology of diabetes mellitus
  Aneurysms
  Non-invasive techniques for the assessment of
  arteries and veins
9 RESISTANCE BLOOD VESSELS
  Introduction
  Resistance to blood flow
  Vascular smooth muscle
  Local control of vascular smooth muscle
  Hormonal control of blood vessel diameter
  Autonomic nervous system and peripheral circulation
  control
  Special circulations
10 ARTERIAL BLOOD PRESSURE
  Introduction
  Arterial baroreceptors
  Cardiopulmonary reflexes
  Chemoreceptor reflexes
  Measurement of arterial blood pressure
  Pathological consequences ised arterial
  pressure
  Treatment of hypertension
  Hydrostatic pressure in the circulation
11 CAPILLARY FUNCTION AND THE LYMPHATIC SYSTEM
  Structure of capillaries
  Movement of substances across capillary walls
  Water movement across capillary walls
  The lymphatic system
  Oedema
12 FETAL CARDIOVASCULAR SYSTEM AND CONGENITAL HEART DISEASE
  Intoduction
  How does the transition from fetal to adult circulation
  occur?
  The normal ECG in childhood
  Congenital heart disease
  Early and late management of congenital heart
  disease
13 EXERCISE AND THE CARDIOVASCULAR SYSTEM
  Physiological responses to exercise
  Dynamic (isotonic) exercise
  Oxygen debt and the recovery from exercise
  Cardiovascular responses to static exercise
  Training effects of exercise
  Cardiovascular health benefits of exercise
  Clinical uses of exercise testing
14 HAEMORRHAGE AND CIRCULATORY SHOCK
  Introduction
  Arterial blood pressure changes in response to
  haemorrhage
  Short-term responses which help to restore lost blood
  volume
  Longer term responses which help to restore lost
  blood volume and electrolytes
  Decompensated or irreversible shock following
  haemorrhage
  Causes of shock
  Fluid replacement therapy
Glossary
Ind